If you are using the legacy VMware vSphere Client on Windows 10 you may have some issues with the VM console that display only a part of the screen and leave blank other parts. You can use other clients (like the Web Client if you have vCenter or the Host UI if you have at least ESXi 6.0U2), but maybe you will have other issues (for example on ESXi 6.0 host UI console mouse may not work well or not at all).